Crocetin-Diazirine

Diazirine-Cricetin is a photocrosslinked natural product probe constructed by directionally coupling the aryl bis (aziridine) photosensitive group to the crocetin core. It retains the core biological activities of crocetin, such as myocardial protection and neuroprotection, while relying on the photo covalent capture property of bis (aziridine) to achieve precise targeting of weak interactions and instantaneous binding of target proteins in living cells. It is a core tool molecule in the field of chemical biology research of polyene dicarboxylic acid natural products.

msds of Crocetin-Diazirine